Isatuximab for Relapsed/Refractory T-Cell Acute Lymphoblastic Leukemia

We are studying whether Isatuximab can safely help adults with relapsed or refractory T-cell acute lymphoblastic leukemia achieve remission. This trial looks at its effects alone and with other chemotherapy drugs.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Bortezomib Eg
Bortezomib Eg is a cancer medicine used to treat multiple myeloma and certain types of lymphoma.
Cytarabine
Sarclisa
Sarclisa is a medicine used to treat multiple myeloma, a type of blood cancer.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Bortezomib
Bortezomib is a substance that blocks cellular protein breakdown to treat certain blood cancers, including multiple myeloma.
Cyclophosphamide
Cyclophosphamide is a cancer-fighting and immune-suppressing substance used to treat various cancers and some severe autoimmune conditions.
Cytarabine
Cytarabine is a chemotherapy substance used to treat certain blood cancers, especially acute leukemias.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Abormib
Adabonib
Alexan

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Technische Universitaet Dresden
Medizinische Klinik und Poliklinik I
Dresden, Germany
Universitaetsklinikum Duesseldorf AöR
Department of Hematology, Oncology and Clinical Immunology
Düsseldorf, Germany
Universitaetsklinikum Erlangen AöR
Department of Medicine 5
Erlangen, Germany

Sponsor: Goethe University Frankfurt
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.