Chronic Graft Versus Host Disease
Chronic graft versus host disease (cGVHD) is a condition that can occur after a stem cell or bone marrow transplant, where the donated immune cells attack the recipient's body, leading to various symptoms.
Itacitinib: Continued Treatment Study
We are providing ongoing treatment for participants who have benefited from itacitinib in earlier studies. This study aims to evaluate the safety of continued use of this medication.
Efficacy phase (II)Post-Trial Drug AccessNo PlaceboCost ReimbursementInvestigational MedicinesOralHematologyInternal MedicineOncology
What diseases are being studied?
Health conditions and diseases that the clinical trial is designed to study and treat.
Bronchiolitis Obliterans Syndrome
Bronchiolitis obliterans syndrome (BOS) is a serious lung condition that can develop after a lung transplant, characterized by inflammation and scarring of the small airways, leading to breathing difficulties.
Myelofibrosis
Myelofibrosis is a rare bone marrow disorder that disrupts the body's normal production of blood cells, leading to severe anemia, fatigue, and an enlarged spleen.
Who can participate in the clinical trial?
These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..
- Are you currently pregnant or breastfeeding?
- Do you have any serious health problems that your doctor has not controlled?
- Are you able to access itacitinib therapy through regular means (not through a clinical trial)?
- Are you willing to avoid pregnancy or fathering children during the study?
- Are you able to comply with scheduled visits and treatment plans?
What experimental substances are being tested?
Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.
Itacitinib
Where is the clinical trial being conducted?
Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.
Loading map...
Ordensklinikum Linz GmbH
Hämatologie mit stammzelltransplantation, Hämostatseologie und medizinische Onkologie
Linz, Austria
UZ Leuven
Pneumology
Heverlee, Belgium
Martin-Luther-Universitaet Halle-Wittenberg
Department of Internal Medicine IV (Hematology and Oncology)
Halle (Saale), Germany
Sponsor: Incyte Corp.
Last updated: Nov 26, 2025
Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.