Ivosidenib for Acute Myeloid Leukemia After Stem Cell Transplant

We are studying whether Ivosidenib can help patients with acute myeloid leukemia or high-risk myelodysplastic neoplasia stay healthy after a stem cell transplant. This trial focuses on those with an IDH1 mutation to see if it improves their chances of remaining disease-free.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Tibsovo
Tibsovo is a cancer medicine used to treat certain types of leukemia and bile duct cancer.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Ivosidenib
Ivosidenib is a cancer-targeting substance used to treat cancers that have an IDH1 gene mutation, especially acute myeloid leukemia.

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Klinikum Chemnitz gGmbH
Klinik für Innere Medizin III
Chemnitz, Germany
Technische Universitaet Dresden
Medizinische Klinik und Poliklinik I
Dresden, Germany
Universitaetsklinikum Essen AöR
Klinik für Hämatologie und Stammzelltransplantation
Essen, Germany

Sponsor: Technische Universitat Dresden
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.