Karonudib for Blood Cancers: Phase 1 Study

We are evaluating the safety and tolerability of Karonudib in patients with advanced blood cancers like Acute Myeloid Leukemia and Multiple Myeloma. This study aims to find the best dose and understand how well it works with other cancer treatments.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Karon

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Alprostadil
Alprostadil is a substance that widens blood vessels to increase blood flow, used for erectile dysfunction and to keep a newborn’s heart vessel open.
Idarubicin Hydrochloride
Idarubicin hydrochloride is a chemotherapy substance used to treat certain cancers, especially acute leukemias.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Th1579

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Alprestil
Alprostadil Altan
Alprostadil Altan Pharma

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Rigshospitalet
Department of Hematology Phase-1-Unit
Copenhagen, Denmark
Aarhus Universitet
Department of Haematology
Gjellerup, Denmark
Cancer Center Karolinska
Phase 1 Unit, Center for Clinical Cancer Studies Tema Cancer Studiebehandlingsenheten
Stockholm, Sweden
Sponsor: Oxcia AB
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.