Kidney Disease: ALE.F02 Treatment Study

We are testing a new intravenous treatment, ALE.F02, for patients with rapidly progressive glomerulonephritis linked to AAV. The study aims to see if it can help protect kidney function and assess its safety.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Ludea
Testolan

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Cyclophosphamide
Cyclophosphamide is a cancer-fighting and immune-suppressing substance used to treat various cancers and some severe autoimmune conditions.
Lixisenatide
Lixisenatide is a substance that helps lower blood sugar in people with type 2 diabetes by increasing insulin release and slowing digestion.
Omeprazole
Omeprazole is a substance that reduces stomach acid to relieve heartburn and treat acid-related stomach and esophagus problems.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Lixudebart

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Acidcare
Agastin 20 Mg
Albosan

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Institute For Clinical And Experimental Medicine
Transplant Centre and Nephrology
Prague, Czechia
Vseobecna Fakultni Nemocnice V Praze
Klinika nefrologie
Prague, Czechia
Aalborg University Hospital
Department of Nephrology
Aalborg, Denmark

Sponsor: Alentis Therapeutics AG
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.