Kidney Function: Vonafexor Study

We are studying the effects of vonafexor on kidney function in people with impaired renal function and suspected MASH. The trial will help us understand how different doses impact kidney health and safety.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Efexor
Efexor is a medicine used to treat depression and certain anxiety disorders.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Iohexol
Iohexol is a contrast agent used to enhance X-ray and CT images by highlighting blood vessels and organs.
Rosuvastatin
Rosuvastatin is a substance that lowers high cholesterol to help reduce the risk of heart attack and stroke.
Venlafaxine Hydrochloride
Venlafaxine hydrochloride is a substance used to treat depression and some anxiety disorders by helping balance brain chemicals that affect mood.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Alventa
Amphero Xl
Apclaven Xl

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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PROFIL Institut fuer Stoffwechselforschung GmbH
Neuss, Germany
Sponsor: ENYO Pharma
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.