Kidney Protection: Cilastatin vs. Thiosulfate

We are comparing cilastatin and thiosulfate to see which better protects kidneys during surgery with chemotherapy for cancer patients. This study aims to reduce kidney damage after the procedure.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Imipenem/Cilastatin Kabi
Imipenem/Cilastatin Kabi is an antibiotic used to treat serious bacterial infections.
Sodium Thiosulfate Hope Pharmaceuticals
A medicine used as an antidote for cyanide poisoning.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Cilastatin
Cilastatin is a substance that protects the kidneys and prevents breakdown of certain antibiotics to maintain their effectiveness.
Cilastatin Sodium
Cilastatin sodium is a substance that prevents kidney breakdown of certain antibiotics, protecting the kidneys and prolonging the antibiotics' effectiveness.
Imipenem
Imipenem is an antibiotic substance used to treat serious bacterial infections by killing or stopping the growth of bacteria.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Andatin
Imicilast
Imicilex

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

Loading map...
Hospital General Universitario Gregorio Maranon
Cirugía General
Ciudad Lineal, Spain
Sponsor: Fundacion Para La Investigacion Biomedica Del Hospital Gregorio Maranon
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.