Kidney Transplant: Belatacept vs. Calcineurin Inhibitors

We are studying whether switching to a new immunosuppressive medication helps adolescent kidney transplant recipients maintain their health better than staying on their current treatment. This trial focuses on patients aged 12 to under 18 years.

>2 years>20 visitsConfirmation phase (III)Post-Trial Drug AccessNo PlaceboPartially RemoteStandard MedicinesOralInjectionInternal MedicineNephrology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Tacrolimus
Tacrolimus is a medicine that suppresses the immune system to help prevent organ transplant rejection and to treat severe eczema.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Belatacept
Belatacept is a substance that suppresses the immune response to help prevent rejection of transplanted organs, especially kidney transplants.
Ciclosporin
Ciclosporin is a substance that suppresses the immune system to prevent organ transplant rejection and treat autoimmune conditions.
Tacrolimus
Tacrolimus is a substance that suppresses the immune system to prevent organ transplant rejection and treat certain inflammatory conditions like severe eczema.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Adoport
Adport
Advagraf

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Universitair Ziekenhuis Gent
Paediatric Nephrology
Ledeberg, Belgium
Pellegrin Hospital
Service Nephrologie pediatrique
Bordeaux, France
Hospices Civils De Lyon
Service de Nephrologie Rhumatologie Dermatologie Pediatrique
Bron, France
Sponsor: Bristol-Myers Squibb Services Unlimited Company
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.