Kidney Transplant: Imlifidase for Highly Sensitized Children

We are studying whether imlifidase can help children with high sensitization receive a kidney transplant by improving compatibility with the donor. This trial will also look at kidney function and overall safety of the treatment.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Idefirix
Idefirix is a medicine that removes antibodies to help people with kidney failure receive a donated kidney.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Anti-T Lymphocyte Immunoglobulin For Human Use
Anti-T lymphocyte immunoglobulin is a preparation of antibodies that reduces activity of immune T cells to prevent or treat organ transplant rejection.
Imlifidase
Imlifidase is a substance that rapidly breaks down IgG antibodies to reduce rejection risk and enable organ transplantation.
Immunoglobulin G
Immunoglobulin G is a blood protein that helps the body recognize and neutralize germs to provide immune protection.

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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HUS Helsinki University Hospital
New Children's Hospital
Helsinki, Finland
Robert Debre University Hospital
Nephrology
Le Pré-Saint-Gervais, France
Hospital Universitari Vall D Hebron
Paediatric Nephrology
Barcelona, Spain

Sponsor: Hansa Biopharma AB
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.