Kidney Transplant: Regulatory T Cell Therapy

We are studying the safety of using regulatory T cells in kidney transplant recipients to see if it helps the body accept the new kidney better. This may allow for less reliance on standard immunosuppressive medications.

Safety phase (I)Efficacy phase (II)No PlaceboPartially RemoteInvestigational MedicinesOralInjectionInternal MedicineNephrology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Advagraf
Advagraf is a medicine used to prevent organ rejection in people who have received a kidney, liver, or heart transplant.
Ampho-Moronal
Cellcept
Cellcept is a medicine that helps prevent a transplanted organ from being rejected by the immune system.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Amphotericin B
Amphotericin B is a substance that treats serious systemic fungal infections.
Anti-T Lymphocyte Immunoglobulin For Human Use
Anti-T lymphocyte immunoglobulin is a preparation of antibodies that reduces activity of immune T cells to prevent or treat organ transplant rejection.
Dimetindene Maleate
Dimetindene maleate is a substance that blocks histamine to relieve allergic symptoms like itching, hives, runny nose, and watery eyes.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Treg

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

4-In-One Flu Relief
6 Years Plus Paracetamol Boots
Abacat

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Charite Universitaetsmedizin Berlin KöR
Chirurgische Klinik CCM|CVK
Berlin, Germany
Sponsor: Charite Universitaetsmedizin Berlin KöR
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.