Kidney Transplantation: Donor Modified Immune Cells

We are studying whether using specially modified immune cells can help patients tolerate their new kidney better than standard treatments. The trial also looks at the safety of this new approach in preventing infections and other complications.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Micol

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Galantamine
Galantamine is a substance used to help improve memory and thinking in people with mild to moderate Alzheimer’s disease.
Miconazole
Miconazole is a substance that treats fungal infections of the skin and mucous membranes such as athlete's foot and yeast infections.
Mitomycin
Mitomycin is a substance that treats certain cancers by stopping cancer cells from growing and dividing.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Acumor Xl
Aneprosil
Bergal Sr

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Charite Universitaetsmedizin Berlin KöR
Medizinische Klinik mit Schwerpunkt Nephrologie und Internistische Intensivmedizin; Campus Virchow
Berlin, Germany
University Medical Center Hamburg-Eppendorf
Universitäres Transplantations Centrum
Hamburg, Germany
Universitaetsklinikum Heidelberg AöR
Innere Medizin V; Klinik für Hämatologie, Onkologie, Rheumatologie
Heidelberg, Germany

Sponsor: TolerogenixX GmbH
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.