Knee Osteoarthritis: Genicular Arteries Embolization Study

We are investigating whether a new procedure can help reduce knee pain in people with symptomatic knee osteoarthritis. Participants will compare this treatment to a sham procedure to assess its effectiveness.

>2 years6-10 visitsConfirmation phase (III)Partially RemoteStandard MedicinesInjectionInternal MedicineOrthopedics and Traumatology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Heparine Choay
Heparine Choay is a blood-thinning medicine used to prevent and treat blood clots.
Lipiodol Ultra Fluide
Lipiodol Ultra Fluide is an oil-based contrast agent doctors use to help show organs and vessels on X-ray imaging.
Optiray
Optiray is a contrast dye used during imaging scans to help doctors see organs and blood vessels more clearly.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Anhydrous Lidocaine Hydrochloride
Anhydrous Lidocaine Hydrochloride is a local anesthetic substance used to numb skin and tissues for minor procedures or relieve localized pain.
Ethyl Esters Of Iodised Fatty Acids From Poppyseed Oil
Ethyl esters of iodised fatty acids from poppyseed oil is an oil-based contrast substance used to make organs and vessels visible on X-rays.
Heparin Sodium
Heparin sodium is a substance that helps prevent and treat blood clots by reducing the blood's ability to clot.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Acido Clodronico Doc Generici
Acoin
Aescin

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

Loading map...
Assistance Publique Hopitaux De Paris
Rhumatologie
Créteil, France
Assistance Publique Hopitaux De Paris
Radiologie Interventionnelle Vasculaire et Oncologique
Issy-les-Moulineaux, France
Assistance Publique Hopitaux De Paris
Médecine physique et réadaptation
Maison Blanche, France
Sponsor: Assistance Publique Hopitaux De Paris
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.