Knee Surgery: Testing SRSD107 for Blood Clot Prevention

We are studying whether SRSD107 can effectively prevent blood clots in adults undergoing knee replacement surgery. We will also assess how safe it is compared to the standard treatment, enoxaparin.

6-12 months6-10 visitsEfficacy phase (II)Cost ReimbursementPartially RemoteInvestigational MedicinesInjectionCardiologyOrthopedics and Traumatology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Clexane
Clexane is a medicine that helps prevent and treat harmful blood clots.
Sodium Chloride Injection Fresenius
Sodium Chloride Injection Fresenius is a sterile salt-water IV solution used to hydrate patients and replace lost fluids and salts.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Enoxaparin Sodium
Enoxaparin sodium is a substance that helps prevent and treat blood clots by thinning the blood.
Sodium Chloride
Sodium chloride is a substance used to replace salts and fluids in the body and to clean or irrigate wounds and nasal passages.
Sodium Chloride Solution 0.9%
Sodium chloride 0.9% is a sterile salt solution used to replace fluids and electrolytes, hydrate patients, and clean wounds or body cavities.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Srsd107

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Acuolens
Addex Natriumklorid
Aminoplasmal E

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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University Multiprofile Hospital For Active Treatment And Emergency Medicine N I Pirogov
First Clinic of Orthopaedics and Traumatology
Pernik, Bulgaria
University Multiprofile Hospital For Active Treatment Saint Georgi EAD
Clinic of Orthopaedics and Traumatology
Plovdiv, Bulgaria
Multiprofile Hospital For Active Treatment - Shumen AD
Department Orthopaedics and Traumatology
Shumen, Bulgaria
Sponsor: Sirius Therapeutics Inc.
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.