Large Incisional Hernia: Botulinum Toxin A Injection Study

We are investigating whether injecting botulinum toxin A before surgery helps reduce complications and improve recovery for patients with large incisional hernias. This study compares the effects of BTA to a placebo injection.

>2 yearsConfirmation phase (III)Cost ReimbursementStandard MedicinesInjectionGastroenterologyOrthopedics and Traumatology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Xeomin
Xeomin is a medicine used to relax certain muscle spasms and temporarily reduce frown lines between the eyebrows.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Botulinum Toxin Type A For Injection Ph. Eur.
Botulinum toxin type A is a substance that temporarily relaxes muscles to reduce spasms and soften facial wrinkles.
Clostridium Botulinum Neurotoxin Type A (150kd)
Clostridium botulinum neurotoxin type A is a substance that temporarily blocks nerve signals to relax muscles and reduce unwanted muscle activity.
Free Of Complexing Proteins

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Bocouture
Xeomeen
Бокотюр

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Centre Hospitalier D Auxerre
Chirurgie digestive et générale
Auxerre, France
Centre Hospitalier Universitaire De Bordeaux
Chirurgie vasculaire et endovasculaire
Bordeaux, France
Assistance Publique Hopitaux De Paris
Chirurgie viscérale et digestive
Colombes, France
Sponsor: Assistance Publique Hopitaux De Paris
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.