Lennox-Gastaut Syndrome
Lennox-Gastaut syndrome (LGS) is a severe form of epilepsy that usually starts in childhood, characterized by multiple types of seizures, cognitive impairment, and developmental delays.
Lennox-Gastaut Syndrome: Carisbamate Treatment Study
We are investigating whether carisbamate can help reduce drop seizures in children and adults with Lennox-Gastaut Syndrome. This study will also look at the safety and tolerability of the medication.
What diseases are being studied?
Health conditions and diseases that the clinical trial is designed to study and treat.
Who can participate in the clinical trial?
These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..
- Are you between 4 and 55 years old?
- Do you have Lennox-Gastaut syndrome with at least one drop seizure (a seizure that could cause you to fall)?
- Are you currently taking 1 to 4 anti-seizure medications like Keppra, Lamictal, or Depakote at a stable dose?
- Are you pregnant, breastfeeding, or planning to become pregnant?
- Have you had any serious health issues, like a heart problem or major surgery, in the last 12 months?
What experimental substances are being tested?
Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.
Carisbamate
Where is the clinical trial being conducted?
Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.
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Universitaetsklinikum Erlangen AöR
Neurologische Klinik, Epilepsiezentrum
Erlangen, Germany
Epilepsiezentrum Kleinwachau gGmbH
Kleinwachau Sächsisches Epilepsiezentrum Radeberg
Radeberg, Germany
Iaso Private General Obstetrics Gynecological & Pediatric Clinic Diagnostic Therapeutic & Research Center S.A.
Department of Pediatric Neurology
Efpálio, Greece
Sponsor: Sk Life Science Inc.
Last updated: Nov 27, 2025
Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.