Leukemia and Lymphoma: Dasatinib and Venetoclax Study for Children

We are testing two new drugs for children with relapsed or refractory leukemia or lymphoma that have specific genetic mutations. The goal is to assess safety and see if these drugs can effectively treat their condition.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Sprycel
Sprycel is a medicine used to treat certain types of blood cancer, including chronic myeloid leukemia and some acute lymphoblastic leukemia.
Venclyxto
Venclyxto is a medicine used to treat certain types of blood cancer, including some forms of leukemia and lymphoma.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Dasatinib
Dasatinib is a substance that treats certain blood cancers by blocking abnormal signals that make cancerous white blood cells grow.
Venetoclax
Venetoclax is a substance used to treat certain blood cancers by helping cancer cells die.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Daruph
Daruph®
Dasa-Abz

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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St. Anna Kinderspital GmbH
Department of Hematology, Oncology and Immunology
Vienna, Austria
Universitair Ziekenhuis Gent
Paediatric Haemato-oncology
Ledeberg, Belgium
Rigshospitalet
Department of Paediatrics and Adolescent Medicine
Copenhagen, Denmark

Sponsor: Princess Maxima Center For Pediatric Oncology
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.