Liver Transplant: Regulatory T Cell Therapy

We are studying a new treatment using regulatory T cells for liver transplant recipients to see if it is safe and allows them to stop taking tacrolimus. We also want to learn how it affects graft function and patients' quality of life.

Safety phase (I)Efficacy phase (II)No PlaceboInvestigational MedicinesOralInjectionHepatologyInfectious Diseases

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Advagraf
Advagraf is a medicine used to prevent organ rejection in people who have received a kidney, liver, or heart transplant.
Envarsus
Envarsus is a medicine used to help prevent the body from rejecting a transplanted kidney.
Paracetamol Ratiopharm
Paracetamol Ratiopharm is a pain reliever and fever reducer used for headaches, minor aches, and fever.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Dimetindene Maleate
Dimetindene maleate is a substance that blocks histamine to relieve allergic symptoms like itching, hives, runny nose, and watery eyes.
Paracetamol
Paracetamol is a substance that relieves pain and reduces fever.
Tacrolimus
Tacrolimus is a substance that suppresses the immune system to prevent organ transplant rejection and treat certain inflammatory conditions like severe eczema.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Treg02

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

4-In-One Flu Relief
6 Years Plus Paracetamol Boots
Abacat

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

Loading map...
Charite Universitaetsmedizin Berlin KöR
Department of Surgery CCM-CVK
Berlin, Germany
Sponsor: Charite Universitaetsmedizin Berlin KöR
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.