Localized Ocular Melanoma: IDE196 Treatment Study

We are testing the investigational drug IDE196 to see if it can shrink tumors in patients with localized ocular melanoma before surgery. The study aims to evaluate its safety and effectiveness in improving treatment outcomes.

11-15 visitsEfficacy phase (II)No PlaceboInvestigational MedicinesOralOncologyOphthalmology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Metformin Hydrochloride
Metformin hydrochloride is a medicine that helps lower blood sugar in people with type 2 diabetes.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Ethinylestradiol
Ethinylestradiol is a synthetic estrogen substance used mainly in hormonal contraceptives to prevent pregnancy and regulate menstrual cycles.
Metformin Hydrochloride
Metformin hydrochloride is a substance that helps lower blood sugar in people with type 2 diabetes.
Norethisterone
Norethisterone is a synthetic hormone substance used to regulate menstrual cycles, treat menstrual disorders, and provide contraception.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Ide196
Darovasertib

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Abmetfina Xr
Adimet
Adimet Xr

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Institut Curie
Unité d'Investigation Clinique Adulte
Paris, France
Universitaetsklinikum Essen AöR
Innere Klinik (Tumorforschung)
Essen, Germany
Charite Universitaetsmedizin Berlin KöR
Klinik für Augenheilkunde
Teltow, Germany
Sponsor: Ideaya Biosciences Inc.
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.