Recalcitrant Lower Limb Nonunion
Recalcitrant lower limb nonunion is a condition where a fracture in the lower limb does not heal properly, leading to ongoing pain and disability despite treatment efforts.
Lower Limb Nonunion: NVD-003 Implant Study
We are testing a new 3D bone implant for adults with nonunion fractures in the lower limb. The study aims to evaluate its safety and effectiveness in promoting healing and improving quality of life.
1-2 years6-10 visitsSafety phase (I)Efficacy phase (II)No PlaceboCost ReimbursementInvestigational MedicinesOrthopedics and Traumatology
What diseases are being studied?
Health conditions and diseases that the clinical trial is designed to study and treat.
Who can participate in the clinical trial?
These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..
- Are you at least 18 years old?
- Do you have a body mass index (BMI) between 20 and 40 kg/m²?
- Are you currently pregnant or breastfeeding?
- Are you taking any medications that affect bone health, like steroids or blood thinners?
- Do you have poorly controlled diabetes with a blood sugar level above 10%?
What experimental substances are being tested?
Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.
Nvd003
Autologous Adipose-Derived Stem Cells
Where is the clinical trial being conducted?
Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.
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Grand Hopital De Charleroi
Orthopedics and traumatology
Charleroi, Belgium
Chirec
Orthopeady
Etterbeek, Belgium
Chu Brugmann
Orthopedic surgery
Jette, Belgium
Sponsor: Novadip Biosciences
Last updated: Nov 27, 2025
Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.