Lower Limb Trauma: Rivaroxaban vs. Heparin

We are studying whether Rivaroxaban is as effective as low-molecular weight heparin in preventing blood clots in patients with lower limb injuries. This trial is for those at high risk of complications while in a cast or brace.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Fragmine
Fragmin is a medicine used to prevent and treat blood clots.
Fraxiparine
Fraxiparine is a medicine that helps prevent and treat blood clots by thinning the blood.
Innohep®
Innohep is a medicine used to prevent and treat dangerous blood clots in the legs or lungs.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Dalteparin Sodium
Dalteparin sodium is a blood thinner used to prevent and treat harmful blood clots.
Enoxaparin Sodium
Enoxaparin sodium is a substance that helps prevent and treat blood clots by thinning the blood.
Fondaparinux Sodium
Fondaparinux sodium is a substance used to prevent and treat blood clots by reducing the blood's ability to form clots.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Inhixa

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Aban
Agublon
Arovi

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Centre Hospitalier Universitaire D'Angers
Département de Médecine d'Urgence
Angers, France
Centre Hospitalier Victor Dupouy
Service d'Urgence
Argenteuil, France
Centre Hospitalier General D'Arpajon
Département de médecine d'urgence
Arpajon, France

Sponsor: Centre Hospitalier Universitaire D'Angers
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.