Lung Cancer: Enhanced Skin Care Management

We are studying if improved skin care can help reduce skin side effects in patients with advanced EGFR-mutated lung cancer receiving amivantamab and lazertinib. This trial compares enhanced care to standard skin management.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Clobegalen
Dalacin T Topical Lotion
Dalacin T Topical Lotion is a skin medicine used to treat acne by helping reduce pimples and prevent new breakouts.
Dociton

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Amivantamab
Amivantamab is a substance that targets specific proteins on certain lung cancer cells to help control advanced non-small-cell lung cancer with EGFR exon 20 mutations.
Chlorhexidine
Chlorhexidine is an antiseptic substance used to kill germs on skin and in the mouth to help prevent or treat infections.
Chlorhexidine Digluconate Solution
Chlorhexidine digluconate solution is an antiseptic substance used to kill germs on skin and in the mouth to help prevent infection.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Jnj-73841937
Jnj-61186372

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Acnatac
Actidox
Actidox

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Centre Hospitalier Universitaire De Nice
Département de pneumologie et d'oncologie thoracique
Nice, France
Institut Curie
Pneumology
Paris, France
Assistance Publique Hopitaux De Marseille
Oncologie multidisciplinaire et innovations thérapeutiques
Septèmes-les-Vallons, France

Sponsor: Janssen - Cilag International
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.