Lung Cancer Treatment: Divarasib and Pembrolizumab

We are studying a new treatment combination for patients with advanced non-small cell lung cancer that has a specific genetic mutation. The goal is to see if this new approach improves survival and quality of life compared to standard treatments.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Budenofalk
Budenofalk is a medicine used to reduce inflammation in the gut, treating conditions like Crohn’s disease and other inflammatory bowel disorders.
Carbo-Cell
Carboplatin Bendalis
Carboplatin Bendalis is a chemotherapy medicine used to treat various types of cancer.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Budesonide
Budesonide is a steroid substance that reduces inflammation in the airways to help control asthma and other respiratory conditions.
Carboplatin
Carboplatin is a chemotherapy substance used to treat various cancers by damaging cancer cells and slowing tumor growth.
Cisplatin
Cisplatin is a substance used in chemotherapy to kill or stop the growth of cancer cells.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Ro 743-5846
Divarasib

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Acorspray
Aeromax
Airbudenid

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Azorg
Pneumology
Aalst, Belgium
UZ Brussel
Oncology
Ganshoren, Belgium
Jessa Ziekenhuis
Oncology
Hasselt, Belgium

Sponsor: F. Hoffmann-La Roche AG
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.