Lung Cancer Treatment: MK-2870 with Pembrolizumab

We are comparing a new combination treatment for metastatic non-small cell lung cancer to standard therapy. This study aims to see if the combination improves survival and quality of life for patients with high PD-L1 levels.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Keytruda
Keytruda is a cancer medicine that helps the immune system find and fight tumor cells.
Paracetamol
Paracetamol relieves pain and reduces fever for conditions like headaches, muscle aches, and colds.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Acetylsalicylic Acid
Acetylsalicylic acid is a substance that reduces pain, fever, and inflammation and can help prevent blood clots.
Betamethasone Sodium Phosphate Ph. Eur
Betamethasone sodium phosphate is a substance that reduces inflammation and calms the immune system.
Caffeine
Caffeine is a substance that stimulates the brain to increase alertness and reduce tiredness.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Mk-2870

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

4-In-One Flu Relief
6 Years Plus Paracetamol Boots
Abacat

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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University Hospital Olomouc
Klinika plicních nemocí a tuberkulózy
Olomouc, Czechia
Nemocnice AGEL Ostrava-Vitkovice a.s.
Plicní oddělení
Ostrava, Czechia
Multiscan s.r.o.
Onkologické a radiologické centrum
Pardubice, Czechia

Sponsor: Merck Sharp & Dohme LLC
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.