Lupus Nephritis: LNP023 Treatment Study

We are studying the safety and effectiveness of LNP023 in adults with active lupus nephritis. The goal is to see if it helps improve kidney function compared to standard treatments.

1-2 years 11-15 visits Efficacy phase (II)Post-Trial Drug Access Investigational Medicines Oral InjectionNephrologyRheumatology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Prednisone Eg

Prednisone Eg is a steroid medicine that reduces inflammation and treats allergic, autoimmune, and other inflammatory conditions.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Iptacopan

Iptacopan is a substance that blocks part of the immune complement system to prevent red blood cell destruction in certain rare blood disorders.

Lidocaine Hydrochloride Monohydrate

Lidocaine hydrochloride monohydrate is a local anesthetic substance used to numb skin and tissues for minor procedures and pain relief.

Methylprednisolone

Methylprednisolone is a corticosteroid that reduces inflammation and calms an overactive immune system.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

LNP023

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Brucorten

Cison

Cortancyl

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Assistance Publique Hopitaux De Paris

2022: Service de Néphrologie

Issy-les-Moulineaux, France

Centre Hospitalier Regional De Marseille

2024: Centre de Néphrologie et Transplantation Rénale

Marseille, France

Centre Hospitalier Universitaire De Nantes

2020: Service médical Néphrologie – Immunologie Clinique - Transplantation

Nantes, France

Sponsor: Novartis Pharma AG

Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.