Mantle Cell Lymphoma: Loncastuximab Tesirine Treatment

We are studying whether loncastuximab tesirine can improve outcomes for patients with relapsed or refractory mantle cell lymphoma after immunochemotherapy. The trial also looks at the safety of this treatment and its effectiveness in reducing disease presence.

Efficacy phase (II)No PlaceboStandard MedicinesInjectionHematologyOncology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Bendamustine
Bendamustine is a chemotherapy medicine used to treat certain blood cancers, such as lymphoma and some types of leukemia.
Cytarabine

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Bendamustine
Bendamustine is a substance used to treat certain cancers, especially non-Hodgkin lymphoma and chronic lymphocytic leukemia.
Bendamustine Hydrochloride
Bendamustine hydrochloride is a chemotherapy substance used to treat certain blood cancers by killing cancer cells.
Cytarabine
Cytarabine is a chemotherapy substance used to treat certain blood cancers, especially acute leukemias.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Alexan
Ara-Cell
Aracytin

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

Loading map...
Azienda Ospedaliero-Universitaria Ss Antonio E Biagio E Cesare Arrigo
SCDU Ematologia
Alessandria, Italy
Azienda Socio Sanitaria Territoriale Degli Spedali Civili Di Brescia
SC Ematologia
Brescia, Italy
ASST Grande Ospedale Metropolitano Niguarda
SC Ematologia
Bresso, Italy
Sponsor: Fondazione Italiana Linfomi Ets
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.