Marfan Syndrome
Marfan Syndrome is a genetic disorder that affects the body's connective tissue, leading to features such as tall stature, long limbs, and an increased risk of cardiovascular problems like aortic aneurysms.
Marfan Syndrome: Valsartan for Aortic Health
We are studying whether valsartan can slow down aortic root dilatation in children and young adults with Marfan syndrome. The trial will measure changes in aortic size and related health outcomes.
>2 years11-15 visitsConfirmation phase (III)Partially RemoteStandard MedicinesOralCardiologyInternal Medicine
What diseases are being studied?
Health conditions and diseases that the clinical trial is designed to study and treat.
Loeys-Dietz Syndrome
Loeys-Dietz Syndrome is a genetic condition that affects connective tissue, leading to features similar to Marfan syndrome, including a risk of aortic aneurysms and other cardiovascular issues.
Ehlers-Danlos Syndrome
Ehlers-Danlos Syndrome is a group of disorders affecting connective tissues, characterized by hyper-flexible joints, skin that can be easily bruised, and a risk of cardiovascular complications.
Shprintzen-Goldberg Syndrome
Shprintzen-Goldberg Syndrome is a rare genetic disorder that affects connective tissue and can lead to craniofacial abnormalities and cardiovascular issues.
Arterial Tortuosity Syndrome
Arterial Tortuosity Syndrome is a rare connective tissue disorder characterized by tortuous arteries and a predisposition to vascular complications.
Who can participate in the clinical trial?
These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..
- Are you between 1 and 39 years old?
- Do you have a diagnosis of Marfan Syndrome or related conditions?
- Are you currently pregnant, breastfeeding, or planning to become pregnant in the next 12 months?
- Are you taking blood pressure medications like Valsartan (Diovan) or Lisinopril (Prinivil, Zestril)?
- Do you have heart failure, defined as a left ventricular ejection fraction less than 40%?
What similar medicines might you know?
Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.
Almertan
Almertan
Alsartir
Where is the clinical trial being conducted?
Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.
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Krakowski Szpital Specjalistyczny im. Jana Pawła II
Instytut Kardiologii, Uniwersytet Jagielloński Collegium Medicum
Kraków, Poland
Instytut Centrum Zdrowia Matki Polki
Instytut Centrum Zdrowia Matki Polki
Łódź, Poland
Uniwersyteckie Centrum Kliniczne Warszawskiego Uniwersytetu Medycznego
I Katedra i Klinika Kardiologii Warszawskiego Uniwersytetu Medycznego
Ochota, Poland
Sponsor: Medical University Of Gdansk
Last updated: Nov 26, 2025
Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.