Medulloblastoma Treatment: MEMMAT Trial

We are studying a combination of anti-cancer drugs for children with recurrent brain tumors. The goal is to see if this treatment improves response rates and overall survival.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Avastin
Avastin is a cancer medicine used to slow tumor growth by stopping tumors from getting new blood vessels.
Celebrex
Celebrex is a medicine used to relieve pain and inflammation from arthritis and other painful conditions.
Celecoxib
Celecoxib is a medicine used to reduce pain and swelling from arthritis and other short-term painful conditions.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Bevacizumab
Bevacizumab is a substance that blocks formation of new blood vessels to treat certain cancers and eye conditions caused by abnormal vessel growth.
Celecoxib
Celecoxib is a substance that reduces pain and inflammation, commonly used to treat arthritis and other inflammatory conditions.
Cyclophosphamide
Cyclophosphamide is a cancer-fighting and immune-suppressing substance used to treat various cancers and some severe autoimmune conditions.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Eto-GRY
Ara-cell
Thalidomide

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Abevmy
Aclexa
Aclexa

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Medical University Of Graz
Klinische Abteilung für Pädiatrische Hämatologie/Onkologie
Graz, Austria
Medizinische Universitaet Innsbruck
Department für Kinder- und Jugendheilkunde
Innsbruck, Austria
Johannes Kepler University Linz
Universitätsklinik für Kinder –u. Jugendheilkunde, MedCampus IV
Linz, Austria

Sponsor: Medical University Of Vienna
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.