MEN1703 for Aggressive B-cell Non-Hodgkin Lymphoma

We are studying the safety and effectiveness of MEN1703 alone and with glofitamab in patients with relapsed or refractory aggressive B-cell non-Hodgkin lymphoma. This research aims to find better treatment options for this challenging cancer.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Columvi
Columvi is a cancer medicine used to treat certain B‑cell lymphomas, a type of blood cancer, when other treatments have failed.
Gazyvaro
Gazyvaro is a cancer medicine used to treat certain blood cancers, including some types of lymphoma and chronic lymphocytic leukemia.
Lenalidomide Sandoz 25 Mg Hard Capsules
Lenalidomide Sandoz 25 mg hard capsules is a cancer medicine used to treat certain blood cancers, including multiple myeloma and some types of lymphoma.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

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Glofitamab
Glofitamab is a lab-made antibody that helps the immune system target and kill abnormal B cells in certain types of B-cell lymphoma.
Lenalidomide
Lenalidomide is a substance that helps treat certain blood cancers by affecting the immune system to stop cancer growth.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Men1703
Dibromo nitro piperidinyl benzimidazole

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

7,5 Mg Stada
Agrocia
Alocutan

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Centre Hospitalier Universitaire De Bordeaux
Hôpital Haut-Lévêque-Centre François Magendie-Service d'Hématologie Clinique et Thérapie Cellulaire
Canéjan, France
Centre Hospitalier Le Mans
Centre de Cancérologie de la Sarthe
Coulaines, France
Centre Hospitalier Et Universitaire De Limoges
CHU Dupuytren 1 - Service d’Hématologie Clinique et Thérapie Cellulaire
Isle, France

Sponsor: Ryvu Therapeutics S.A.
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.