Menière's Disease: Methylprednisolone Injection Study

We are investigating whether an injection of methylprednisolone can reduce vertigo attacks in patients with Menière's disease. This study will also assess its effects on hearing and overall quality of life.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Dexamethason Cf
Dexamethason Cf is a steroid medicine used to reduce inflammation and treat allergic reactions and other immune-related conditions.
Kenacort-A 40
Kenacort-A 40 is a steroid medicine used to reduce inflammation and relieve symptoms like swelling, pain, and allergic reactions.
Natriumchlorid 0,9 %
Natriumchlorid 0,9% is a sterile salt solution used to replace fluids, hydrate patients, and deliver medicines into a vein.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Dexamethasone
Dexamethasone is a steroid that reduces inflammation and suppresses the immune system to treat allergic, inflammatory, and autoimmune conditions.
Domperidone
Domperidone is a substance that helps relieve nausea and vomiting by speeding up stomach emptying and improving gut movement.
Gentamicin
Gentamicin is an antibiotic used to treat serious bacterial infections, especially those caused by gram-negative bacteria.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Acuolens
Adcortyl Intra-Articular / Intradermal Injection
Adcortyl Intra-Articular/Intradermal

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Gelre Hospitals
Otorhinolaryngology
Apeldoorn, Netherlands
Medisch Spectrum Twente
Otorhinolaryngology
Enschede, Netherlands
Leiden University Medical Center
Otorhinolaryngology and head and neck surgery
Leiden, Netherlands

Sponsor: Leiden University Medical Center
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.