Meningioma Treatment: Everolimus and 177Lu-DOTATATE

We are studying a new combination treatment for patients with grades 2 and 3 refractory meningioma. The goal is to see if this approach can help improve survival and manage tumor growth.

1-2 years 11-15 visits Efficacy phase (II)No Placebo Cost Reimbursement Partially Remote Standard Medicines Oral InjectionNeurologyOncology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Everolimus Puren

Everolimus Puren is a medicine used to treat some types of cancer and to help prevent organ transplant rejection.

Lutathera

Lutathera is a targeted radiation medicine used to treat certain neuroendocrine tumors that start in the digestive system or pancreas.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Everolimus

Everolimus is a substance that suppresses the immune system to prevent organ rejection and helps slow growth of certain cancers.

Lutetium (177lu) Oxodotreotide

Lutetium-177 oxodotreotide is a radioactive substance that delivers targeted radiation to certain neuroendocrine tumors.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Aderolio

Aderolio 250 Mcg Tablets

Aderolio 500 Mcg Tablets

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Centre Hospitalier Universitaire De Bordeaux

Nuclear Medicine Unit

Bordeaux, France

Centre Hospitalier Regional Et Universitaire De Brest

Nuclear Medicine Unit

Brest, France

Hospices Civils De Lyon

Nuclear Medicine Unit

Bron, France

Sponsor: CHRU De Nancy

Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.