Metastatic Colorectal Cancer: S 95005 with Bevacizumab

We are studying a new treatment combination for patients with metastatic colorectal cancer who cannot receive intensive therapy. The goal is to see if it helps patients live longer without disease progression compared to standard treatment.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Avastin
Avastin is a cancer medicine used to slow tumor growth by stopping tumors from getting new blood vessels.
Lonsurf
Lonsurf is a cancer medicine used to treat advanced colorectal and stomach cancers when other treatments have failed.
Xeloda
Xeloda is an oral chemotherapy medicine used to treat certain cancers, including colorectal and breast cancer.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Bevacizumab
Bevacizumab is a substance that blocks formation of new blood vessels to treat certain cancers and eye conditions caused by abnormal vessel growth.
Capecitabine
Capecitabine is a substance that helps stop certain cancers from growing, commonly used for breast and colorectal cancer.
Tipiracil
Tipiracil is a substance used alongside an anti-cancer agent to help treat advanced colorectal and stomach cancers by boosting the agent's effectiveness.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Abevmy
Alymsys
Avzivi

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Region Midtjylland
Oncology department
Herning, Denmark
Specjalistyczny Szpital Onkologiczny Nu-Med Sp. z o.o.
Pododdzial Chemioterapii
Tomaszów Mazowiecki, Poland
Vychodoslovensky Onkologicky Ustav a.s.
Oddelenie klinickej onkologie
Košice, Slovakia

Sponsor: Institut De Recherches Internationales Servier IRIS
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.