Metastatic Non-Small Cell Lung Cancer
Metastatic Non-Small Cell Lung Cancer (NSCLC) is a type of lung cancer that has spread from the lungs to other parts of the body, often leading to serious health issues.
Metastatic Non-Small Cell Lung Cancer: ONC-392 vs. Docetaxel
We are studying a new treatment, ONC-392, to see if it helps patients with metastatic non-small cell lung cancer who have progressed on immunotherapy. The goal is to compare its effectiveness and safety against the standard treatment, docetaxel.
What diseases are being studied?
Health conditions and diseases that the clinical trial is designed to study and treat.
Who can participate in the clinical trial?
These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..
- Are you at least 18 years old?
- Do you have a confirmed diagnosis of metastatic squamous lung cancer?
- Are you currently taking steroids like Prednisone or Dexamethasone at more than 10 mg per day?
- Have you had any cancer treatment side effects that have not improved to grade 1 or lower?
- Do you have a life expectancy of at least 3 months?
What experimental substances are being tested?
Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.
Humanised IgG1 Monoclonal Antibody Against CD152
Where is the clinical trial being conducted?
Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.
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Az Maria Middelares Gent
Pulmonology
Gent, Belgium
Jessa Ziekenhuis
Pulmonology
Hasselt, Belgium
Centre Hospitalier Regional De La Citadelle
Pulmonology
Liège, Belgium
Sponsor: Oncoc4 Inc.
Last updated: Nov 27, 2025
Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.