Metastatic Pancreatic Cancer: Valproic Acid and Simvastatin Study

We are studying whether adding valproic acid and simvastatin to standard chemotherapy improves treatment for patients with metastatic pancreatic cancer. This trial also looks at safety and quality of life for participants.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Abraxane
Abraxane is a chemotherapy medicine used to treat several types of cancer, including breast, lung, and pancreatic cancer.
Capecitabine
Capecitabine is a chemotherapy medicine used to treat certain cancers, including breast and colon cancer.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Capecitabine
Capecitabine is a substance that helps stop certain cancers from growing, commonly used for breast and colorectal cancer.
Cisplatin
Cisplatin is a substance used in chemotherapy to kill or stop the growth of cancer cells.
Gemcitabine
Gemcitabine is a substance that slows or stops cancer cell growth and is used to treat several cancers, including pancreatic and lung.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Capecel
Capecitabin Al
Capecitabin Amarox

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

Loading map...
Azienda Ospedaliero Universitaria Ospedali Riuniti
medical oncology
Foggia, Italy
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
U.O.C. Oncologia Medica
La Massimina-Casal Lumbroso, Italy
Ospedale Vito Fazzi Lecce
ONCOLOGIA MEDICA
Lecce, Italy

Sponsor: IRCCS Istituto Nazionale Tumori Fondazione Pascale
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.