Metastatic Prostate Cancer: ProBio Study

We are investigating if treatment choices based on biomarker signatures can improve survival and quality of life for patients with metastatic prostate cancer. This study compares these personalized approaches to standard care.

6-10 visits Confirmation phase (III)Post-Trial Drug Access No Placebo Investigational Medicines Oral InjectionOncologyUrology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Abiraterone

Abiraterone is a medicine used to treat prostate cancer by lowering male hormones that can make the cancer grow.

Cabazitaxel

Cabazitaxel is a chemotherapy medicine used to treat advanced prostate cancer after other treatments have stopped working.

Nubeqa

Nubeqa is a medicine used to treat prostate cancer that continues to grow despite hormone therapy before it has visibly spread.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Abiraterone

Abiraterone is a substance that reduces testosterone production to help manage advanced prostate cancer.

Abiraterone Acetate

Abiraterone acetate is a substance that lowers the body's male hormones to slow the growth of prostate cancer.

Anhydrous Docetaxel

Anhydrous Docetaxel is a substance used to treat various cancers by stopping cancer cells from dividing.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Bay 1841788

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Abaxan

Abibam®

Abinone

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Onze-Lieve-Vrouwziekenhuis

Oncology

Aalst, Belgium

GasthuisZusters Antwerpen

Oncology

Berchem, Belgium

CHU Helora

Oncology

Fayt-lez-Manage, Belgium

Sponsor: Karolinska Institutet

Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.