Metastatic Urothelial Carcinoma: Livmoniplimab and Budigalimab Study

We are studying a new combination of livmoniplimab and budigalimab for adults with metastatic urothelial carcinoma who have not responded to prior treatments. The goal is to see if this combination improves survival compared to standard chemotherapy.

Efficacy phase (II)Post-Trial Drug Access No Placebo Cost Reimbursement Partially Remote Investigational Medicines InjectionOncology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Taxotere

Taxotere is a cancer medicine used to treat several types of cancer by slowing or stopping cancer growth.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Docetaxel

Docetaxel is a chemotherapy substance used to treat various cancers by stopping cancer cells from dividing.

Gemcitabine

Gemcitabine is a substance that slows or stops cancer cell growth and is used to treat several cancers, including pancreatic and lung.

Paclitaxel

Paclitaxel is a substance used in chemotherapy to treat various cancers by preventing cancer cells from dividing.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Budigalimab

Livmoniplimab

Paclitaxel

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Bendadocel

Camitotic

Demotaxel

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Az Maria Middelares Gent

Oncology

Gent, Belgium

UZ Leuven

Oncology

Heverlee, Belgium

Institut Jules Bordet

Oncology

Negenmanneke, Belgium

Sponsor: AbbVie Deutschland GmbH & Co. KG

Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.