Mpox Booster Vaccine: Fractional vs. Full Dose

We are studying whether a smaller booster dose of the MVA-BN vaccine is as effective as the standard dose in adults. This trial will also look at the safety and immune response of both doses.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Imvanex
Imvanex is a vaccine used to prevent smallpox and monkeypox infections.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Modified Vaccinia Ankara – Bavarian Nordic Live Virus
Modified Vaccinia Ankara – Bavarian Nordic is a live viral vaccine used to prevent smallpox and monkeypox.

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

Loading map...
GGD Amsterdam
CSGA
Amsterdam, Netherlands
Leiden University Medical Center
Infectious Diseases
Leiden, Netherlands
GGD Haaglanden
Infectieziektenbestrijding
Scheveningen, Netherlands
Sponsor: Academisch Ziekenhuis Leiden
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.