Multiple Myeloma: CC-92480 Combination Study

We are exploring a new treatment combination for people with relapsed or refractory multiple myeloma. The study aims to assess safety and how well it works compared to standard treatments.

Safety phase (I)Efficacy phase (II)No Placebo Investigational Medicines OralHematologyOncology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Dexamethason Galen

Dexamethason Galen is a steroid medicine used to reduce inflammation and treat severe allergies or immune-related conditions.

Dexamethason Jenapharm

Dexamethason Jenapharm is a medicine that reduces swelling and eases allergic or immune reactions and other serious health problems.

Dexamethason Ratiopharm

Dexamethason Ratiopharm is a steroid medicine used to reduce inflammation and calm an overactive immune response in conditions like allergies and arthritis.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Dexamethasone

Dexamethasone is a steroid that reduces inflammation and suppresses the immune system to treat allergic, inflammatory, and autoimmune conditions.

Trametinib

Trametinib is a substance that treats certain cancers by blocking cell signals that cause cancer cells to grow.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Mekinist

Tazemetostat

Mezigdomide

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Amelinor

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Oslo University Hospital HF

Oslo Myeloma Center

Oslo, Norway

Institut Catala D'oncologia

Hematology

Badalona, Spain

Hospital Universitario Marques De Valdecilla

Hematology

Santander, Spain

Sponsor: Celgene Corp.

Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.