Multiple Myeloma: HUVR-CARTemis-1 T-Cell Therapy

We are studying a new T-cell therapy for patients with multiple myeloma who have relapsed after an allogeneic transplant. The trial aims to evaluate the safety and effectiveness of this treatment over time.

>2 yearsSafety phase (I)Efficacy phase (II)No PlaceboInvestigational MedicinesOralInjectionHematologyOncology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Allopurinol
Allopurinol is a medicine that lowers uric acid to prevent and treat gout and certain kidney stones.
Paracetamol
Paracetamol relieves pain and reduces fever for conditions like headaches, muscle aches, and colds.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Allopurinol
Allopurinol is a substance that lowers uric acid levels to prevent gout attacks and related complications.
Cetuximab
Cetuximab is a substance that targets a protein on cancer cells to help slow or stop growth in colorectal and head and neck cancers.
Cyclophosphamide
Cyclophosphamide is a cancer-fighting and immune-suppressing substance used to treat various cancers and some severe autoimmune conditions.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Chimeric Receptor
T Lymphocytes

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

4-In-One Flu Relief
6 Years Plus Paracetamol Boots
Abacat

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Hospital De La Santa Creu I Sant Pau
Hematology & Hemotherapy
Fraga, Spain
University Hospital Virgen Del Rocio S.L.
Hematology & Hemotherapy
Huelva, Spain
Hospital Universitario De Salamanca
Hematology & Hemotherapy
Salamanca, Spain
Sponsor: Fundacion Publica Andaluza para la Gestion de la Investigacion en Salud de Sevilla (FISEVI)
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.