Multiple Myeloma: Isatuximab Combination Therapy

We are studying a new treatment combining isatuximab with other medications for patients with newly diagnosed multiple myeloma who cannot undergo a transplant. The goal is to see how effective and safe this treatment is, and how it impacts patients' lives.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Revlimid
Revlimid is a cancer medicine used to treat certain blood cancers and bone marrow disorders, including multiple myeloma.
Sarclisa
Sarclisa is a medicine used to treat multiple myeloma, a type of blood cancer.
Velcade
Velcade is a medicine used to treat certain blood cancers such as multiple myeloma and mantle cell lymphoma.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Bortezomib
Bortezomib is a substance that blocks cellular protein breakdown to treat certain blood cancers, including multiple myeloma.
Dexamethasone
Dexamethasone is a steroid that reduces inflammation and suppresses the immune system to treat allergic, inflammatory, and autoimmune conditions.
Isatuximab
Isatuximab is a substance that helps the immune system target and destroy cancerous plasma cells in multiple myeloma.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

7,5 Mg Stada
Abormib
Adabonib

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Centre Hospitalier Universitaire D'Angers
Maladies du sang
Angers, France
Centre Hospitalier Annecy Genevois
Hématologie
Annecy, France
Centre Hospitalier De La Cote Basque
Hématologie
Bayonne, France

Sponsor: Centre Hospitalier Universitaire De Poitiers
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.