Multiple Myeloma: Mezigdomide vs. Pomalidomide

We are studying whether a new drug, mezigdomide, combined with bortezomib and dexamethasone, is more effective than pomalidomide with the same drugs for patients with relapsed or refractory multiple myeloma.

≤3 months >20 visits Confirmation phase (III)Post-Trial Drug Access No Placebo Cost Reimbursement Investigational Medicines Oral InjectionHematologyOncology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Dexamethason Cf

Dexamethason Cf is a steroid medicine used to reduce inflammation and treat allergic reactions and other immune-related conditions.

Dexamethason Galen

Dexamethason Galen is a steroid medicine used to reduce inflammation and treat severe allergies or immune-related conditions.

Dexamethason Jenapharm

Dexamethason Jenapharm is a medicine that reduces swelling and eases allergic or immune reactions and other serious health problems.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Bortezomib

Bortezomib is a substance that blocks cellular protein breakdown to treat certain blood cancers, including multiple myeloma.

Dexamethasone

Dexamethasone is a steroid that reduces inflammation and suppresses the immune system to treat allergic, inflammatory, and autoimmune conditions.

Pomalidomide

Pomalidomide is a substance used to treat certain blood cancers by helping control abnormal plasma cell growth and modulating the immune system.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Cc-92480

Mezigdomide

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Abormib

Adabonib

Amelinor

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Universitaetsklinikum Krems

Clinical Department for Internal Medicine II

Krems an der Donau, Austria

Steiermaerkische Krankenanstalten Ges.m.b.H.

Department for Hemato-Oncology

Leoben, Austria

Noe LGA Gesundheit Region Mitte GmbH

Clinical Department for Internal Medicine I

Sankt Pölten, Austria

Sponsor: Celgene Corp.

Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.