Multiple Myeloma: Treatment-Free Interval Study

We are exploring whether a treatment-free interval is safe and effective for newly diagnosed multiple myeloma patients receiving a combination of Daratumumab, Lenalidomide, and Dexamethasone. The study aims to compare the effects of continuous treatment versus a break in therapy.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Darzalex
Darzalex is a medicine used to treat multiple myeloma, a type of blood cancer.
Lenalidomide
Lenalidomide is a medicine used to treat certain blood cancers and bone marrow disorders, including multiple myeloma.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Daratumumab
Daratumumab is a substance that helps treat multiple myeloma, a blood cancer, by directing the immune system to attack the cancerous plasma cells.
Dexamethasone
Dexamethasone is a steroid that reduces inflammation and suppresses the immune system to treat allergic, inflammatory, and autoimmune conditions.
Lenalidomide
Lenalidomide is a substance that helps treat certain blood cancers by affecting the immune system to stop cancer growth.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

7,5 Mg Stada
Cortedal
Ferulinor

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Jeroen Bosch Ziekenhuis
Hematology
's-Hertogenbosch, Netherlands
Noordwest Ziekenhuisgroep Stichting
Hematolgy
Alkmaar, Netherlands
Ziekenhuisgroep Twente Stichting
Interne geneeskunde
Almelo, Netherlands

Sponsor: Stichting Hemato-Oncologie voor Volwassenen Nederland (Hovon)
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.