Multiple Myeloma: Venetoclax and Dexamethasone Study

We are investigating whether a combination of venetoclax and dexamethasone is effective for patients with relapsed and refractory multiple myeloma who have the translocation (11;14). This study aims to find out if this treatment can improve outcomes for these patients.

>2 years 6-10 visits Efficacy phase (II)Investigational Medicines Oral InjectionHematologyOncology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Pneumovax

Pneumovax is a vaccine that helps prevent pneumonia and other infections caused by pneumococcal bacteria.

Pneumovax 23

Pneumovax 23 is a vaccine that helps protect adults and some children from pneumonia and other serious infections caused by pneumococcal bacteria.

Prevenar 13

Prevenar 13 is a vaccine that helps protect infants, children, and adults from serious infections like pneumonia, meningitis, and ear infections caused by bacteria.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Dexamethasone

Dexamethasone is a steroid that reduces inflammation and suppresses the immune system to treat allergic, inflammatory, and autoimmune conditions.

Pneumococcal Polysaccharide Serotype 1

Pneumococcal polysaccharide serotype 1 is a vaccine component that helps the immune system prevent infections caused by pneumococcus serotype 1.

Pneumococcal Polysaccharide Serotype 1 Conjugated To Crm197 Adsorbed On Aluminium Phosphate

Pneumococcal polysaccharide serotype 1 conjugated to CRM197 adsorbed on aluminium phosphate is a vaccine component that helps protect against pneumococcal serotype 1 infections.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Dexamethasone

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Pneumovax®

Prevenar 20

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Rigshospitalet

Hematology

Copenhagen, Denmark

Odense University Hospital

Hematology

Odense, Denmark

Lillebaelt Hospital

Hematology

Vejle, Denmark

Sponsor: Lillebaelt Hospital

Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.