Multiple Sclerosis in Kids: Ofatumumab and Siponimod Study

We are comparing two new treatments, ofatumumab and siponimod, to fingolimod in children with multiple sclerosis. The study aims to see if these new options are as effective and safe for managing their condition.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Fingolimod
Fingolimod is a substance that helps reduce relapses and slow disability in people with relapsing multiple sclerosis.
Fingolimod Hydrochloride
Fingolimod hydrochloride is a substance that reduces relapses and slows disability progression in relapsing multiple sclerosis.
Ofatumumab
Ofatumumab is a lab-made antibody that targets and reduces certain immune B cells to treat relapsing multiple sclerosis and some blood cancers.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

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Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Medical University Of Vienna
1011 : Deaprtment Neurology
Vienna, Austria
Universitair Ziekenhuis Gent
1140 : Pediatry
Ledeberg, Belgium
Centre hospitalier universitaire de Liege
1141 : Neurology
Tilff, Belgium

Sponsor: Novartis Pharma AG
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.