Muscle Invasive Bladder Cancer: New Treatment Combination

We are studying a combination of three medications for patients with muscle invasive bladder cancer who cannot take cisplatin. The goal is to see if this approach can effectively shrink tumors before surgery.

Efficacy phase (II)No PlaceboInvestigational MedicinesInjectionInternal MedicineOncologyUrology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Trodelvy
Trodelvy is a cancer medicine used to treat certain advanced or metastatic breast and bladder cancers.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Sacituzumab Govitecan
Sacituzumab govitecan is an antibody-based cancer treatment that targets tumor cells and delivers a cell-killing agent to shrink certain advanced cancers.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Zimberelimab
Domvanalimab

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Institut Catala D'oncologia
Oncology
Badalona, Spain
Hospital Universitario De Navarra
Oncology
Barañáin, Spain
Hospital Clinico Universitario De Valladolid
Oncology
Cistérniga, Spain
Sponsor: Fundacion Para El Progreso De La Oncologia En Cantabria
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.