Chronic Myelomonocytic Leukaemia
Chronic Myelomonocytic Leukaemia (CMML) is a type of cancer that starts in blood-forming cells of the bone marrow and invades the blood. It is characterized by an increase in monocytes, a type of white blood cell.
Myelodysplastic Syndromes: Oral ASTX030 vs. Subcutaneous Azacitidine
We are studying a new oral treatment for patients with myelodysplastic syndromes, chronic myelomonocytic leukemia, or acute myeloid leukemia. The trial aims to evaluate its safety and how it compares to the standard subcutaneous treatment.
What diseases are being studied?
Health conditions and diseases that the clinical trial is designed to study and treat.
Acute Myeloid Leukaemia
Acute Myeloid Leukaemia (AML) is a fast-growing cancer of the blood and bone marrow that results in an overproduction of immature white blood cells. It can lead to severe complications if not treated promptly.
Myelodysplastic Syndrome
Myelodysplastic Syndrome (MDS) is a group of disorders caused by poorly formed or dysfunctional blood cells. It can lead to ineffective blood cell production and may progress to acute leukaemia.
Who can participate in the clinical trial?
These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..
- Are you 18 years of age or older?
- Do you have confirmed myelodysplastic syndrome (MDS) or chronic myelomonocytic leukemia (CMML)?
- Have you had any major surgery in the past 3 weeks?
- Do you have an active uncontrolled infection or serious health condition?
- Are you currently taking any medications that you know you are allergic to, like azacitidine or cedazuridine?
What similar medicines might you know?
Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.
Azacitdine Clonmel
Azacitidin
Azacitidin Aliud
Where is the clinical trial being conducted?
Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.
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Fakultni Nemocnice Brno
Interní hematologická a onkologická klinika
Brno, Czechia
Fakultni Nemocnice Ostrava
Klinika Hematoonkologie FNO a LF OU
Hlučín, Czechia
Fakultni Nemocnice Kralovske Vinohrady
Hematologická klinika
Prague, Czechia
Sponsor: Taiho Oncology Inc.
Last updated: Nov 27, 2025
Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.