Post-Polycythaemia Vera Myelofibrosis
Post-Polycythaemia Vera Myelofibrosis is a rare blood disorder that develops in some patients after they have had polycythemia vera, leading to scarring of the bone marrow and affecting blood cell production.
Myelofibrosis: Study of Pacritinib vs. Standard Treatment
We are investigating whether pacritinib can better reduce spleen size and improve symptoms in patients with myelofibrosis. This trial is for those with severe low platelet counts and compares pacritinib to physician's choice of therapy.
What diseases are being studied?
Health conditions and diseases that the clinical trial is designed to study and treat.
Primary Myelofibrosis
Primary Myelofibrosis is a rare type of blood cancer that disrupts the body's normal production of blood cells, leading to severe anemia, fatigue, and an enlarged spleen.
Post-Essential Thrombocythaemia Myelofibrosis
Post-Essential Thrombocythaemia Myelofibrosis is a rare condition that can occur in patients who have had essential thrombocythemia, resulting in bone marrow scarring and complications in blood cell production.
Who can participate in the clinical trial?
These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..
- Are you at least 18 years old?
- Do you have a platelet count of less than 50,000/μL?
- Are you currently taking blood thinners like Warfarin, Eliquis, or Xarelto?
- Are you pregnant or breastfeeding?
- Have you had any major bleeding in the last 3 months?
What experimental substances are being tested?
Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.
Pacritinib
What similar medicines might you know?
Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.
Adelcort®
Alpicort
Alpicort E
Where is the clinical trial being conducted?
Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.
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University Multiprofile Hospital For Active Treatment Dr. Georgi Stranski EAD
Clinical Hematology Clinic
Pleven, Bulgaria
University Multiprofile Hospital For Active Treatment Saint Georgi EAD
Clinical Hematology Clinic
Plovdiv, Bulgaria
Military Medical Academy
Hematology Clinic
Sofia, Bulgaria
Sponsor: Sobi Inc.
Last updated: Nov 26, 2025
Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.