Myotonic Dystrophy: Long-Term Study of Mexiletine PR

We are examining the long-term safety and effectiveness of mexiletine PR for treating myotonia in patients with myotonic dystrophy types 1 and 2. This study is for those who have completed a prior related study.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Mexiletine Hydrochloride Clinigen Healthcare
A medicine used to treat serious abnormal heart rhythms originating in the heart's lower chambers.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Mexiletine
Mexiletine is a substance used to treat abnormal and potentially dangerous heart rhythms by calming the heart’s electrical activity.
Mexiletine Hydrochloride
Mexiletine hydrochloride is a substance that helps control abnormal heart rhythms, especially ventricular arrhythmias.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Dopital
Namuscla
Ritalmex

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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UZ Leuven
Neurology
Heverlee, Belgium
Aarhus Universitetshospital
Neurologisk Forskning
Århus, Denmark
Rigshospitalet
Neuromuscular Clinic and Research Unit Department 8077
Copenhagen, Denmark

Sponsor: Lupin Atlantis Holdings SA
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.