Nephrogenic Diabetes Insipidus: Amiloride Treatment Study

We are investigating whether amiloride can help patients with nephrogenic diabetes insipidus caused by lithium treatment for bipolar disorder. The study looks at its effects on urine concentration, thirst, and quality of life.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Amiloride
Amiloride is a medicine that helps the body remove extra salt and water while protecting potassium, often used to treat high blood pressure.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Amiloride
Amiloride is a potassium-sparing substance that reduces fluid retention and high blood pressure while helping prevent potassium loss.
Amiloride Hydrochloride Bp
Amiloride hydrochloride is a potassium-sparing diuretic that helps the body remove excess salt and water while conserving potassium.
Anhydrous Amiloride Hydrochloride
Anhydrous amiloride hydrochloride is a potassium-sparing diuretic used to reduce fluid buildup and help lower high blood pressure.

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Assistance Publique Hopitaux De Paris
Service de psychiatrie et addictologie
Colombes, France
Assistance Publique Hopitaux De Paris
Service de Néphrologie
Créteil, France
Assistance Publique Hopitaux De Paris
Service de Psychiatrie et addictologie
Créteil, France

Sponsor: Assistance Publique Hopitaux De Paris
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.