Nerve Damage from Cancer: New Immunotherapy Approach

We are studying a combination of treatments for patients with anti-Hu-associated nerve damage due to cancer. The goal is to see if this early immunotherapy improves symptoms and helps patients live longer without cancer progression.

>2 yearsEfficacy phase (II)No PlaceboInvestigational MedicinesInjectionNeurologyOncology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Cyclophosphamide Sandoz
Cyclophosphamide Sandoz is a chemotherapy medicine used to treat various cancers and some severe autoimmune conditions by suppressing the immune system.
Human Normal Immunoglobulin Pharma Plasma
Human Normal Immunoglobulin Pharma Plasma is a medicine made from donated blood that provides antibodies to help prevent or treat immune system problems.
Mesna Eg
Mesna Eg is a medicine used to protect the bladder from damage caused by certain chemotherapy drugs.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Cyclophosphamide
Cyclophosphamide is a cancer-fighting and immune-suppressing substance used to treat various cancers and some severe autoimmune conditions.
Human Normal Immunoglobulin
Human normal immunoglobulin is a preparation of antibodies from healthy donors used to boost immune protection and treat certain immune-related disorders.
Human Normal Immunoglobulin (Iv)
Human normal immunoglobulin (IV) is a substance made from donated antibodies given intravenously to boost or regulate immune function.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Clairyg

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Beriglobin
Beriglobin P
Beriglobina P

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Centre Hospitalier Universitaire De Toulouse
Neurology
Blagnac, France
Hospices Civils De Lyon
neuro-oncology
Bron, France
Les Hopitaux Universitaires De Strasbourg
Neurology
Eckbolsheim, France
Sponsor: Assistance Publique Hopitaux De Paris
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.