Neuroblastoma: Comparing PET-CT and SPECT-CT Scans

We are studying whether a new PET-CT scan can better detect lesions in patients with neuroblastoma compared to a standard SPECT-CT scan. This may help improve diagnosis and treatment options for patients.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Iobenguane [131i] Pour Thérapie Cis Bio International
Iobenguane [131I] Pour Thérapie is a radioactive medicine used to treat certain hormone-producing tumors, including some adrenal and nerve-related cancers.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Iobenguane
Iobenguane is a radioactive substance used to image and, at higher doses, treat certain neuroendocrine tumors such as neuroblastoma and pheochromocytoma.
Iobenguane (131i)
Iobenguane (131I) is a radioactive substance used to locate and treat certain neuroendocrine tumors.
Iodine (123i) Iobenguane
Iodine-123 iobenguane is a radioactive tracer used in scans to detect certain neuroendocrine tumors and assess heart nerve function.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Meta-fluorobenzylguanidine

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

(131i) Meta-Iodobenzylguanidine For Diagnostic Use Ge Healthcare
[131ι]-Μετα-Ιωδοβενζυλογουανιδίνη Για Διαγνωστικούσ Σκοπούσ Ge Healthcare
[131ι]μετα-Ιωδοβενζυλογουανιδίνη Για Θεραπευτικούσ Σκοπούσ Ge Healthcare

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Princess Maxima Center For Pediatric Oncology
Solid Tumors
De Bilt, Netherlands
Sponsor: Princess Maxima Center For Pediatric Oncology
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.